The Cancer Genome Atlas Data Coordinating Center And Data Portal (TCGADCC/Portal)

The TCGA Project began with a three-year pilot on two cancers, and is currently being scaled up to more than 20 cancers. The program is a collaboration between NCI, NHGRI, and many other cancer research organizations participating as centers in the program. Its goal is to perform the most detailed characterization of cancer ever attempted at the molecular level. Key components of TCGA include the Biospecimen Core Resource (BCR), Cancer Genome Characterization Centers (CGCCs), Genome Sequencing Centers (GSCs), the Data Coordinating Center (DCC), the Genome Data Analysis Centers (GDACs), and the TCGA Data Portal. In this project, SRA provides support through development and operation of the Data Coordinating Center (DCC), whose role is integral to the entire TCGA program. Data is produced within the Centers, including the Genome Sequencing Centers (GSCs), Cancer Genome Characterization Centers (CGCCs), and the Biospecimen Core Resource (BCR). This data is accessible to researchers within and outside TCGA. SRA has also developed a data management pipeline to process data and prepare it for rapid, public distribution in formats and systems that are harmonized with the standards established by the caBIG® program.